Exercise # 10

PRACTICE QUESTIONS

Exercise # 10

Q1. Glycosylated fructosamine test measures glycemic control

a. over the preceding 2 – 3 weeks

b. over the preceding 2 – 3 months- HbA1C

c. over the preceding 1 week

d. Over the preceding 1 month

Q2. Somogyi effect is

a. Increased BG due to prolonged hypoglycemia

b. Also known as rebound hyperglycemia

c. Decreased BG due to prolonged hyperglycemia

d. Also known as rebound hypoglycemia

e. A & B

  

Q3. Who has the authority to determine the Rx products prices in Canada?

a. PMPRB

b. FDC

c. ODB

d. Manufacturing company

Q4.A drug substance with unknown clinical, toxicological, and other properties, is called and is given which name?

a. API ( Active Pharmaceutical Ingredient)

b. NCE ( New Chemical Entity)

c. IND ( Investigational New Drug)

d. NDA ( New drug Application)

Q5.With regards to IND which are correct?

a. IND application is submitted after animal studies

b. Human testing is done only after IND application

c. Phase I tests are done after IND

d. All of the above

Q6.  Large scale multicenter trials, is done in which phase

a. I

b. II

c. III

d. II & III

Q7.  Submission for NDA is done after which phase?

a. I

b. II

c. III

d. IV

Q8.  Which type of molecules have nonzero dipole moments?

a. Non polar molecules that have perfect symmetry

b. Polar molecules that are asymmetric

c. a & b

d. None of the above

Q9.  London dispersed force is also known as

a. Induced dipole – induced dipole interaction

b. dipole – induced dipole interaction

c. Debye induction force ( '' )

d. permanent dipole interaction

Q10. Induced dipole – induced dipole interaction has a force of

a. 0.5 to 1 kcal/mole (London disperse force)

b. 1 to 3 kcal/mole (debye induction force)

c. 1 to 7 kcal/mole (pement dipole interaction-keesom orientation forces)

d. 100 to 200 kcal/mole (ion-ion, ion-dipole…..)

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