Exercise # 19

PRACTICE QUESTIONS

Exercise # 19

Q1. Uric acid is excreted by

a. Kidney

b. GI tract

c. Sweat

d. A & B

e. All of the above

Q2.Urine has a pH of

a. 4 – 5

b. 7 - 9

c. 9 – 11

d. 7.35 to 7.45

Q3. Enzymes involved in Purine metabolism are

a. HGPRT

b. PRPP synthetase

c. XO

d. All of the above

Q4. Which is the enzyme that converts uric acid to Allantoin?

a. Allantoin synthetase

b. Rasburicase (Urate oxidase)

c. Xanthine oxidase

d. None of the above

Q5. What is the relationship of salicylates to Hyperurecemia?

I.      At low doses, they inhibit tubular secretion of uric acid

II.    At high doses, they cause uricosuria

III.  At low doses, they increase plasma levels of uric acid

a. I Only

b. III only

c. I & II only

d. II & III only

e. All of the above

Q6. Which of the following diuretics do not cause hyperurecemia?

a. Spironolactone

b. Triamterene

c. HTCZ

d. CA inhibitors

e. Ethacrynic acid

Q7. Ethambutol and Nicotinic acid increase uric acid level by

a. Displacing uric acid from protein binding sites

b. Competing with urate for tubular secretion sites

c. By enhancing XO enzyme system

d. By a combination of all the above

Q8. MTP and MCP refer to

a. Knuckles of the feet and knuckles of the hands respectively

b. Knuckles of the hand and knuckles of the feet respectively

c. Ankle of the feet and wrist bones of the hands respectively

d. Wrist bones of the hand and ankle of the feet respectively

Ans: A

Q9. What is Podagra?

a. Acute Gout attack of the first metatarsopharyngeal joint is known as podagra.

b. Related to Pyridoxine deficiency

c. When gout attacks parkinsons patients it is known as podagra

d. Gout with DM is known as Podagra

Q10. Colchicine is most effective when given

a. Immediately after symptoms are felt

b. 12 to 36 hrs after symptoms begin

c. 3 days after symptoms begin

d. Along with uricosuric agents in an acute attack

Please correct here for correct answers
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