Exercise # 30

PRACTICE QUESTIONS

Exercise # 30

Q1.  Potent inhibitors of CYP2D6 are

I. Fluoxetine

II. Paroxetine

III.Fluoxamine

a.I only

b.III only

c.I & II only

d.II & III only

e.All of the above

Q2. Venlafaxine at doses greater than 225mg per day can cause

a. Hypertension

b. severe hypotension

c. can lead to paralysis

d. Rebound depression

Q3.  Nefazodone is a potent inhibitor of

a. CYP3A4

b.CYP2D6

c. CYP2C9

d. CYP1A2

Q4.  Which of the following are the mechanisms of action of Mirtazapine?

a. Inhibits presynaptic alpha2 receptors

b. Inhibits 5HT1 receptor

c. Inhibits 5HT2 & 5HT3 receptor

d. all of the above

Q5. Which of the following are least side effects of Mirtazapine?

a. Sexual dysfunction

b. Insomnia

c. Agitation

d. All of the above

e. None of the above

Q6. The receptor which is responsible for weight alteration is

a. H₁

b. 5HT_2c

c. 5HT₂

d. 5HT₃

Q7. Bipolar I disorder is defined as

a. Patient has a history of at least one maniac or mixed episode

b. Patient has never experienced a manic episode, but has experienced one or more depressive episode with at least one hypomanic episode

c. Depressive and hypomanic symptoms persist for two years

d. patient experiences at least 4 depressive, manic, hypomanic, or mixed episode within a 12 month period.

Q8. Cyclothymia is defined as

a. Patient has a history of atleast one maniac or mixed episode

b. Patient has never experienced a manic episode, but has experienced one or more depressive episode with atleast one hypomanic episode

c. Depressive and hypomanic symptoms persist for two years

d. patient experiences atleast 4 depressive, manic, hypomanic, or mixed episode within a 12 month period.

Q9. Bipolar II is defined as a

a. Patient has a history of atleast one maniac or mixed episode

b. Patient has never experienced a manic episode, but has experienced one or more depressive episode with atleast one hypomanic episode

c. Depressive and hypomanic symptoms persist for two years

d. patient experiences atleast 4 depressive, manic, hypomanic, or mixed episode within a 12 month period.

Q10. Rapid cycling is defined as

a. Patient has a history of atleast one maniac or mixed episode

b. Patient has never experienced a manic episode, but has experienced one or more depressive episode with atleast one hypomanic episode

c. Depressive and hypomanic symptoms persist for two years

d. Patient experiences atleast 4 depressive, manic, hypomanic, or mixed episode within a 12 month period.

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