Exercise # 23

PRACTICE QUESTIONS

Exercise # 23

Q1.Increased toxicity of Tramadol is seen when given along with

a. Quinidine

b. Cimetidine

c. SSRI's

d. All of the above

e. B, C only

Q2. COX 2 inhibitors are superior to NSAID's in which of the following

I. Less GI ulceration & Bleeding

II. Fewer effect on platelets

III. Better protection of renal function

a. I Only

b. III only

c. I & II only

d. II & III only

e. All of the above

Q3. Major side effect of hydrochloroqine is

a. Retinopathy

b. Hepatotoxicity

c. Agranulocytosis

d. All of the above

Q4. Mech of action of Leflunomide is

a. Inhibit Pyrimidine synthesis

b. Inhibit purine synthesis

c. Prevent pannus formation

d. B & C only

Q5. Black box warning with Etanercept is for

a. Tuberculosis

b. Immunosuppression

c. Hepatotoxicity

d. Nephrotoxicity

Q6. Bones affected in RA are

a. Metacarpophalengeal Joints ( hand)

b. Proximal Interphalengeal Joints ( hand)

c. Metatorsophalengeal ( foot)

d. Wrists

e. All of the above

Q7. Bones affected in OA are

a. knees

b. Shoulder

c. Pelvic

d. Hands

e. All of the above

Q8. The most commonly found rheumatoid factors are

a. Ig G & Ig A

b. Ig G, Ig M & Ig A

c. Ig M & Ig E

d. Ig M & Ig A

e. Ig E only

Q9. Which of the following are true about biological agents used in RA?

a. Etenercept is a TNF α & b receptor, which binds to TNF, response is seen within 1 to 2 weeks.

b. Infliximab is an antibody against TNF α, and is approved only in combination with MTX

c. Anakinra is a IL 1 receptor antagonist.

d. Etenercept & Infliximab are the shortest acting DMARD.

e. All are correct

Q10. Precipitating factors of an acute asthma exacerbations include

a) allergens( pollen House dust mite, animal dander, mold

b) Occupational hazards( chemical, flour, wood, textile dusts)

c) Exercise

d) Emotions

e) All of the above

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