Exercise # 34

PRACTICE QUESTIONS

Exercise # 34

Q1.  Amantidine causes a diffuse rose color mottling of skin which is known as

a. Erythema multiforme

b. Tinea versicolor

c. Livedo reticularis

d. "Rainbow" coloritis

Q2.  The advantage of Ropinirole/Pramipexole are

a. They have a low potential for motor fluctuations & Dyskinesia

b. When they are given in combination to L Dopa, the latter's dose can be reduced by 27%

c. They are faster acting than any other drugs

d. a & b only.

Q3.  Addition of a COMT inhibitor has what effect on the T_1/2 of levodopa?

a. T_1/2 cannot be altered, so there will be no change

b. T_1/2 is doubled_.

c. T_1/2 is reduced by 35%.

d. T_1/2 is increase by 40 to 50%

Q4.  The combination of L Dopa & Carbidopa is an example of

a. Addition (ex Smx/Tmp)

b. Synergism (ex Penicillin & Aminoglycoside)

c. Potentiation

d. Facilitation

Q5.  With regards to COMT inhibitors with of the following are true?

I. Tolcapone is a central & peripheral inhibitor

II. Tolcapone can cause liver toxicity and rabhdomyolysis

III. Entacapone acts only peripherally

a. I Only

b. III Only

c. I & II only

d. II & III only

e. All

Q6.  Which of the following drugs is indicated as adjunct to carbidopa/levodopa therapy?

a. Pramipexole (can be given as monotherapy)

b. Bromocriptine (adjunct to L – Dopa)

c. Amantadine (adjunct to L - Dopa)

d. Tolcapone

Q7.  Which of the following NT have been believed to cause schizophrenia?

I. Dopamine

II. Serotonin

III.Glutamine

a. I Only

b. III Only

c. I & II only

d. II & III only

e. All

Q8.  Which of the following NT modulates Dopamine activity?

a. 5 HT

b. NE

c. Glutamine

d. Epinephrine

e. GABA

Q9.  Schizophrenia is diagnosed using

a. DSM – IV – TR

b. SMS – IV – TR

c. DSM – III – TR

d. none of the above

Q10.  Which is the fastest acting antiparkinsons drug?

a. Levodopa when given with carbidopa

b. Amantidine

c. Bromocriptine

d. Pramipexole

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