Review Exercise # 42

PRACTICE QUESTIONS

Exercise # 42

Q1. What is the role of NK cells in immunity?

     a. Nk cells are capable of killing Virus infected cells

     b. They are also capable of killing malignant cells

     c. They have to be exposed to IL 2 & IF γ to be activated        to Lymphikine    activated cells before killing.

     d. a & c only

     e. all of the above

Q2. How does NK cell differentiate between Good and infected cells?

     a. They have no differentiation; their disadvantage is that      they kill all cells when activated

     b. KAR (Killer Activating Receptor) helps to identify            infected cells

     c. KIR (Killer Inhibiting Receptor) helps to identify Good        cells

     d. If a target cell expresses MHC Class I molecule it will        not be killed.

     e. all except a.

Q3. Complement contains how many proteins?

     a. 15

     b. 22

     c. 25

     d. 21

     e. 20

Q4. Which complement proteins cause mast cell degranulation?

I. C3

II. C4

III. C5

a. I Only

b. III Only

c. I & II only

d. II & III only

e. All

Q5. What is the function of complement system?

     a. It opsonises bacteria for enhanced phagocytosis

     b. It can recruit and activate various cells

     c. It can participate in regulation of Ab responses, and clearance of Immune    complexes

     d. It can be detrimental to the host

     e. All of the above

Ans: E

Q6. Which of the following are false with regard to immunogens (antigens)?

     a. Lipids are non immunogenic

     b. Proteins are very good immunogens

     c. Polysaccharides are good immunogens

     d. Nucleic acids are poor immunogens

     e. none of the above

Q7. Which of the following are T dependent antigens?

     a. Lipids

     b. Proteins

     c. Polysaccharides

     d. Nucleic acids

     e. none of the above

Q8. Which of the following are T independent antigens?

     a. Lipids

     b. Proteins

     c. Polysaccharides

     d. Nucleic acids

     e. none of the above

Q9. Antibodies are effective against

     a. Extra cellular pathogens

     b. Intracellular pathogens

     c. Both intracellular and extra cellular pathogens

     d. Only against intracellular pathogens inside WBC's

     e. a & d

Q10. Intracellular parasites are killed by

     a. Antibodies

     b. Cell mediated responses

     c. Ab's and Cell mediated responses

     d. Only by NK cells

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